evaluation of serum level of homocysteine, vitamin b12 and zinc in patients with acute ischaemic stroke
(A CASE STUDY OF ZARIA)
Stroke has been a global burden, with increasing morbidity and mortality. Several risk factors have been identified, which include: hyperhomocysteinaemia, hypovitaminosis B12, and low zinc levels, which are the now target of preventive strategies. Limited studies have been done on the risk factors (analytes) in our environment hence the current stu... Continue Reading
evaluation of serum malondialdehyde and vitamin e levels as biomarkers of oxidative stress in hiv/tb co-infected patients
(A CASE STUDY OF KANO, KANO STATE)
Both HIV and Tuberculosis infections are associated with lipid peroxidation and antioxidant imbalance. The Pathology of the two diseases produced free radicals which lead to lipid peroxidation indices one of which is Malondialdehyde (MDA) and to disease progression due to CD4 cells apoptosis. The current study was carried out with the objective of ... Continue Reading
t lymphocyte sub populations, cytokines and pregnancy specific beta-1 glycoprotein in eclampsia
(A CASE STUDY OF KADUNA STATE, NIGERIA)
A comparative cross-sectional study of eclampticand normal healthy pregnant womenconducted in Ahmadu Bello University Teaching Hospital (ABUTH), Shika Zaria to determine Tcell subpopulations (CD3+, CD4+ and CD8+T lymphocytes); cytokines (Tumor necrosis factor[TNF]-?, Interleukin [IL]-2, IL-4, and IL-10) and Pregnancy Specific beta-1 Glycoprotein (P... Continue Reading
serum levels of antioxidant minerals and enzymes among cancer patients
(A CASE STUDY OF ZARIA)
Numerous studies have shown a depletion of antioxidants and increased amount of ROS (reactive oxygen species) in patients with malignancies but no such study have been carried out on the levels of antioxidants in cancer patients in Zariawhich necessitated this study. The overall objective of this study was to measure the serum antioxidant minerals ... Continue Reading
lung function tests among arc welders
(A CASE STUDY OF ZARIA, NORTHERN NIGERIA)
The study of Lung functions among metal Arc welders in Zaria, Nigeria. Aim of the study was to evaluate long-term effects of exposure to welding fumes on lung functions. The metal Arc welders in Zaria study assessed 100 welders and 100 office workers by a questionnaire to record anthropometric data, work history and lung function status by spiromet... Continue Reading
effects of taurine on behavioural, haematological and biochemical responses of mice and wistar rats to restraint stress
The aim of this study was to investigate the effects of taurine administration (100, 200 and 400 mg/kg) on behavioural, haematological and biochemical responses of mice and Wistar rats subjected to acute restraint stress (1 hour/day for 14 days) and chronic restraint stress (6 hour/day for 21 days). The treatments were administered once daily by or... Continue Reading
effects of aqueous extract of alliumcepa (onion) on ciprofloxacin-induced testicular toxicity in wistar rats
This study was carried out to investigate the effects of Allium cepa(onion extract) on ciprofloxacin induced testicular toxicity. Twenty five adult male Wistar rats weighing between 150g �“ 250g assigned randomly to five groups (A-E) were used for this study. The control group (A) received 1 ml of distilled water daily while group B was given 22.8... Continue Reading
relationship between serum fasting insulin concentration and other markers of diabetic control
(A CASE STUDY OF ZARIA)
Diabetes mellitus is a common disease associated with insulin deficiency or resistance. Most studies on diabetes focus on glucose, HbA1c and only a few on fructosamine. Insulin assay was never considered as part of the management of diabetes mellitus. The study was therefore carried out to relate serum fasting insulin level with other markers of gl... Continue Reading
effect of aqueous extract of cowpea (vigna unguiculata) on visuospatial learning and memory in acute lead-induced neurotoxicity in mice
Learning is the act of acquiring new or modifying and re-inforcing existing knowledge, while Memory is relatively the permanent storage of the learned information. Exposure to lead affect brain regions such as hippocampus that are involved in learning and memory. Succimer drug or meso 2,3 �“ Dimercaptosuccinic acid (DMSA) is a metal chelator which... Continue Reading
factors responsible for rejection of polio immunization campaign
(A CASE STUDY OF TARAUNI L.G.A. KANO STATE)
Poliomyelitis is currently the targeted disease to be eradicated by the year 2005 through immunization after eradication of smallpox in the 70s. However vaccine rejection is one of the obstacles for achieving this objective. In this study factors responsible for rejection of OPV (oral polio vaccine) in Tarauni Local Government Area of Kano State we... Continue Reading
comparative neuroanatomical studies on structures of fear response in local breeds of sheep, goat, and dog
This study was designed to compare some fear response structures in three (3) domesticated animals: Sheep (Ovis sp), Goat (Capra sp), and Dog (Canis sp.) and relate it to the different responses of these animals to threats and dangers. Seven (7) dogs, seven (7) goats, and seven (7) sheep were used in this study. The animals were decapitated, their... Continue Reading
effects of senna siamea on the histology and histochemistry of the colon in opoiod-induced constipation in wistar rats
Senna siamea is a medicinal plant native to Asia. It is widely distributed in different parts of Nigeria, where it is employed in traditional ethno-medicinal and ethno-veterinary practices for a variety of ailments. In this study, the effect of S. siamea on smooth muscle contractility of the ileum in an organ-bath was demonstrated as well as evalua... Continue Reading
modulatory effect of piracetam in ischaemic brain injury on the cerebrum, cerebellum and hippocampus of wistar rat
Ischaemic brain injuries, that results from stroke, are common and often lead to permanent residual disabilities. This work investigates the role Piracetam, a nootrophic drug, played in modulation of induced brain injury to key areas of the brain; cerebrum, cerebellum and hippocampus of adult Wistar rats. Drugs like Vitamin C, Vitamin E and cortico... Continue Reading
pattern of first-line anti-tuberculosis drug resistance and associated factors in patients attending national tuberculosis and leprosy training centre and referral hospital zaria
Tuberculosis (TB) is an infectious disease caused by the bacillus Mycobacterium tuberculosis. Despite the availability of Short-course regimens of first-line drugs that can cure around 90% of cases, TB remains a major global health problem causing ill-health among millions of people each year. It ranks as the second leading cause of death from an i... Continue Reading
effect of ethanol on cerebral and cerebellar cortices, neurobehaviour and trace elements of neonatal wistar rats after intrauterine exposure
Alcohol is the most widely used and abused psychoactive drug globally. Ethanol is the main ingredient in the three classes of alcoholic beverages. Children of alcoholic pregnant women are prone to wide spectrum of disorder referred to as Foetal Alcoholic Spectrum Disorder (FASD). The present study aimed at evaluating the teratologic effects of etha... Continue Reading
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