The leaves ofZiziphus mauritiana have been reported to be used in the management of depressive illnesses in traditional medicine. The antidepressant activity of the methanol leaf extract of the plant was evaluated using tail suspension test (TST) and forced swim test (FST) at the doses of 25, 50, 100, and 200 mg/kg.Imipramine (20mg/kg) was used as ... Continue Reading
Lead poisoning is known to cause a number of adverse effects including nephrophaty, infertility, liver, testis and heart damages in human and experimental animals. The toxic effects of lead are treated by chelation therapy whichalso depletes the body store of essential cations and as such there is need to look for alternative therapy to lead poison... Continue Reading
The study of individual variability in pain has become an area of research interest globally. Inter-individual variability in pain perception and response is believed to be due to multiple bio-psycho-social factors, including genetic influences. This study was designed to investigate the influence of sex, age and ethnicity on perception and respons... Continue Reading
Mercury is a ubiquitous and toxic heavy metal which has caused extensive environmental contamination and significant public health problems in many parts of the world and there is increasing evidence that the central nervous system is its main target. The present study evaluated the neurobehavioral, biochemical, and histo-architectural changes foll... Continue Reading
This study was therefore conducted to investigate the prevalence and perception of partner disclosure among HIV positive clients in public health facilities in FCT, Abuja -Nigeria Methods: A cross-sectional survey was conducted among 390 adult HIV clients accessing outpatient care in 10 selected health facilities in Abuja. Prevalence, perception of... Continue Reading
Toxoplasmosis, one of the TORCH’s infections in pregnancy is caused by Toxoplasma gondii an obligate intracellular protozoan parasite which can cause severe complications for an infected mother if the primary infection was acquired during pregnancy. This includes spontaneous abortions, low birth weight, congenital deformities and intrauterine dea... Continue Reading
Hypertension, a non communicable, silent killer disease is of public health significance worldwide. As a public health challenge, hypertension is fast becoming a great concern in Chiroma Community, Lafia with complications such as stroke, kidney failure, heart failure and sudden death. Ill-health associated with hypertension shortens life expectanc... Continue Reading
Salmonella is an important zoonotic pathogen and its prevalence in animals poses a continuous threat to man. A characteristic feature of this organism is its wide host range, which comprises most animal species including mammals, birds and cold-blooded animals in addition to humans. The organism’s route of infection is the faecal-oral route via f... Continue Reading
In Nigeria rabies is endemic and it is an important public health issue that has remained neglected. This is because of the paucity of data to estimate the true status and the public health impact of the disease. Dogs are the major reservoir of the disease and the route of transmission to humans is mainly via bite from a rabid dog. The consumption ... Continue Reading
Population growth and industrialization of the world has dramatically increased the overall environmental load of heavy metals. The effects of pollution by heavy metals are not only an environmental problem but also a public health matter. In this study, raw water samples were collected from two sites (A and B) along river Kubanni, two sites (C and... Continue Reading
The commonest practical use of behavioural tests is probably in the search for new drugs. Medicinal plants have been used in the development of new drugs and continue to play an invaluable role in the drug discovery process. These plants/herbs are relatively cheap and available and their use depends on ancestral experience. The majority of the popu... Continue Reading
Anxiety disorders are mental disorders that share extreme or pathological anxiety as the principal disturbance of mood or emotional tone. This study involved a retrospective analysis of data obtained from hospital records of patients attending clinic at the psychiatry unit of Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria for a two year... Continue Reading
Heavy metal contamination of food crops through irrigation is a major concern due to the potential risk involved. This study was designed to investigate the contamination of food crops grown through irrigation along River Kubanni and Galma, Zaria, with heavy metals (Pb, Cu, Mn, Cd, Cr and Fe). To achieve this, Pb, Cu, Mn, Cd, Cr and Fe concentratio... Continue Reading
The study aims at formulating Paracetamol tablets using Digitaria iburua (DI) starch as binder and disintegrant. Digitaria iburua starch was extracted from Digitaria iburua grains using wet milling and sieving method and thereafter purified. Pregelatinised Digitaria iburua starch (PGS DI) was also prepared. Paracetamol granules were produced by wet... Continue Reading
The variation in human body physique has been a subject of interest to physical anthropologists and human biologists since time immemorial. It is important to understand and analyze the factors associated with body physique, in order to have a better understanding of the morphological structure of the human body. Despite several decades of research... Continue Reading