Anemia is a serious health problem especially in developing countries. In the tropics, rural dwellers had resort to herbal treatment in some cases of anemia. The main aim of this work was to ascertain the role of n-butanol leaf fraction of Telfairia Occidentalis on some haematological parameters in phenyl hydrazine induced anemia in wistar rats. Th... Continue Reading
Lead poisoning is known to cause a number of adverse effects including brain damage, mental impairment and severe behavioural anomalies, impaired cognitive functions in human and experimental animals. The toxic effects of lead are treated by chelation therapy which also depletes the body store of essential cations and as such there is need to look ... Continue Reading
Oxidative stress and lipid peroxidation are central factors in the metabolic dysfunctions and pathologies associated with diabetes. The results from studies on the benefits of Selenium a trace element with antioxidant, anti-lipidemic and anti-inflammatory properties, in diabetes mellitus have been controversial without prospective outcome and Se ap... Continue Reading
The limitations of serum creatinine as a marker of impairment in GFR have led to continuing search for a better marker. Most studies have shown that serum cystatin C may be a more sensitive indicator of glomerular filtration rate (GFR) than serum creatinine in the clinical setting. This study was designed to evaluate serum cystatin C,creatinineand ... Continue Reading
The burden of chronic kidney disease (CKD) is increasing rapidly worldwide and has become a major health issue. Iron deficiency anaemia is one contributory aspect of renal anaemia with increasing morbidity and mortality. Use of iron status markers is integral to assessment of deficiency, and to setting treatment goals in the successful management o... Continue Reading
Stroke has been a global burden, with increasing morbidity and mortality. Several risk factors have been identified, which include: hyperhomocysteinaemia, hypovitaminosis B12, and low zinc levels, which are the now target of preventive strategies. Limited studies have been done on the risk factors (analytes) in our environment hence the current stu... Continue Reading
Both HIV and Tuberculosis infections are associated with lipid peroxidation and antioxidant imbalance. The Pathology of the two diseases produced free radicals which lead to lipid peroxidation indices one of which is Malondialdehyde (MDA) and to disease progression due to CD4 cells apoptosis. The current study was carried out with the objective of ... Continue Reading
A comparative cross-sectional study of eclampticand normal healthy pregnant womenconducted in Ahmadu Bello University Teaching Hospital (ABUTH), Shika Zaria to determine Tcell subpopulations (CD3+, CD4+ and CD8+T lymphocytes); cytokines (Tumor necrosis factor[TNF]-?, Interleukin [IL]-2, IL-4, and IL-10) and Pregnancy Specific beta-1 Glycoprotein (P... Continue Reading
Numerous studies have shown a depletion of antioxidants and increased amount of ROS (reactive oxygen species) in patients with malignancies but no such study have been carried out on the levels of antioxidants in cancer patients in Zariawhich necessitated this study. The overall objective of this study was to measure the serum antioxidant minerals ... Continue Reading
The study of Lung functions among metal Arc welders in Zaria, Nigeria. Aim of the study was to evaluate long-term effects of exposure to welding fumes on lung functions. The metal Arc welders in Zaria study assessed 100 welders and 100 office workers by a questionnaire to record anthropometric data, work history and lung function status by spiromet... Continue Reading
The aim of this study was to investigate the effects of taurine administration (100, 200 and 400 mg/kg) on behavioural, haematological and biochemical responses of mice and Wistar rats subjected to acute restraint stress (1 hour/day for 14 days) and chronic restraint stress (6 hour/day for 21 days). The treatments were administered once daily by or... Continue Reading
This study was carried out to investigate the effects of Allium cepa(onion extract) on ciprofloxacin induced testicular toxicity. Twenty five adult male Wistar rats weighing between 150g �“ 250g assigned randomly to five groups (A-E) were used for this study. The control group (A) received 1 ml of distilled water daily while group B was given 22.8... Continue Reading
Diabetes mellitus is a common disease associated with insulin deficiency or resistance. Most studies on diabetes focus on glucose, HbA1c and only a few on fructosamine. Insulin assay was never considered as part of the management of diabetes mellitus. The study was therefore carried out to relate serum fasting insulin level with other markers of gl... Continue Reading
Learning is the act of acquiring new or modifying and re-inforcing existing knowledge, while Memory is relatively the permanent storage of the learned information. Exposure to lead affect brain regions such as hippocampus that are involved in learning and memory. Succimer drug or meso 2,3 �“ Dimercaptosuccinic acid (DMSA) is a metal chelator which... Continue Reading
Poliomyelitis is currently the targeted disease to be eradicated by the year 2005 through immunization after eradication of smallpox in the 70s. However vaccine rejection is one of the obstacles for achieving this objective. In this study factors responsible for rejection of OPV (oral polio vaccine) in Tarauni Local Government Area of Kano State we... Continue Reading