This study was designed to compare some fear response structures in three (3) domesticated animals: Sheep (Ovis sp), Goat (Capra sp), and Dog (Canis sp.) and relate it to the different responses of these animals to threats and dangers. Seven (7) dogs, seven (7) goats, and seven (7) sheep were used in this study. The animals were decapitated, their... Continue Reading
Senna siamea is a medicinal plant native to Asia. It is widely distributed in different parts of Nigeria, where it is employed in traditional ethno-medicinal and ethno-veterinary practices for a variety of ailments. In this study, the effect of S. siamea on smooth muscle contractility of the ileum in an organ-bath was demonstrated as well as evalua... Continue Reading
Ischaemic brain injuries, that results from stroke, are common and often lead to permanent residual disabilities. This work investigates the role Piracetam, a nootrophic drug, played in modulation of induced brain injury to key areas of the brain; cerebrum, cerebellum and hippocampus of adult Wistar rats. Drugs like Vitamin C, Vitamin E and cortico... Continue Reading
Tuberculosis (TB) is an infectious disease caused by the bacillus Mycobacterium tuberculosis. Despite the availability of Short-course regimens of first-line drugs that can cure around 90% of cases, TB remains a major global health problem causing ill-health among millions of people each year. It ranks as the second leading cause of death from an i... Continue Reading
Alcohol is the most widely used and abused psychoactive drug globally. Ethanol is the main ingredient in the three classes of alcoholic beverages. Children of alcoholic pregnant women are prone to wide spectrum of disorder referred to as Foetal Alcoholic Spectrum Disorder (FASD). The present study aimed at evaluating the teratologic effects of etha... Continue Reading
Malaria remains the most devastating human parasitic infection in the world today. In Nigeria, malaria during pregnancy is responsible for 11% of maternal mortality. There is low coverage and utilization of IPT services in Nigeria. This study was undertaken to investigate the knowledge and utilization of IPT among pregnant women attending ANC in Ji... Continue Reading
Vitamins C and E are naturally present in some foods and are available as dietary supplements. While vitamin C is also known as L-ascorbic acid, vitamin E is a generic name for tocopherols and tocotrienols each with ?, ?, ? and ? subunits. Neurobehavioural models have been used to study behaviour in animals with models specific for each animal spec... Continue Reading
Routine Immunization coverage is generally low in several parts of Nigeria especially the northern region. It is even lower among people who live in hard to reach areas including nomads. Although the exact figures of RI coverage amongst the nomads are not available. There are many cultural/religious beliefs and also physical barriers such as distan... Continue Reading
The effects of vitamin C on some heamatological parameters and biomarkers of oxidative stress in albino wistar rats exposed to lead acetate over a short term (3 weeks) was investigated. Studies have revealed that lead has a wide range of health effects that can result from exposure, and that lead can cause health effects at blood lead levels previo... Continue Reading
Obesity, a state of hyperleptinemia and leptin resistance, may play a role in the aeitiopathogenesis of type 2 diabetes mellitus. Leptin hormone which was originally recognized for its role as a satiety factor has now been implicated in a wide variety of multisystem biological functions, including the regulation of glucose homeostasis. However, the... Continue Reading
Phoenix dactylifera (Date palm) belongs to the family Arecaceae and its leaves, barks, pits, fruits and pollens have anticancer, antioxidant, hepatoprotective, antidiabetic, anti-inflammatory, antibacterial, antifungal and antiviral activities. It is rich in antioxidants, vitamins, steroids, flavonoid, saponins and simple sugars.The aim of the stud... Continue Reading
Lawsonia inermis commonly known as henna has been used traditionally, especially in ayurvedic medicine, for various conditions including liver ailments, and reported to have hepatoprotective properties. This study aims to study the effect of aqueous extract of L. inermis leaves in acute ethanol induced hepatic damage in adult Wistar rats. Thirty (3... Continue Reading
Malaria is endemic in Nigeria with 97% of the population at risk. It accounts for 60% of outpatient visits and 30% of hospitalizations among children under five years of age in Nigeria. Indoor residual spraying (IRS) is one of the major strategies recommended by the World Health Organization (WHO) for malaria control in endemic populations. It play... Continue Reading
Asymptomatic malaria parasitaemia in pregnancy is a major public health challenge responsible for significant morbidity and mortality in endemic areas. In areas with stable malaria transmission like Nigeria, the vast majority of infections with Plasmodium falciparum in pregnancy remain asymptomatic, undetected and untreated with the attendant major... Continue Reading
Immunization is one of the safest and most effective interventions to prevent disease and early child death. Although, about three quarters of the world‘s child population is reached with the required vaccines, only half of the children in Sub-Saharan Africa get access to basic immunization. In Nigeria, only 10% of children in the North West geog... Continue Reading