The purpose of the study was to determine the influence of socio-economic factors and gender on business education students? specialization in Federal Colleges of Education in the North-West Geo-political Zone, Nigeria. The study has four specific objectives; four research questions were raised to guide the study and four null hypotheses were formulated and tested at 0.05 level of significance. The researcher adopted descriptive survey design. The population for the study was 646. The research questions were answered using weighted mean. The weighted mean of 2.5 and above was considered as bench mark for agree while the weighted mean of less than 2.5 was considered as bench mark for disagree. Results of the study showed among others that there was a significant parental influence on students? choice of options in business education. There was also a significant influence on career prospect and students? choice of options in business education. Based on the findings of the study the researcher concluded that socio-economic factors and gender influenced the choice of area of specialization of business education students in federal colleges of education in the north-west geo-political zone, Nigeria It was recommended among, other things, that parents are advised to allow their children to make choice of the area of specialization in business education in Federal Colleges of Education in the North-west zone, on their own without much interferences. Lecturers in the various departments of business education should properly guide the students on the career prospect so that they can make appropriate choice of area of specialization in business education in the Federal colleges of education North-west Geo-political zone, Nigeria