This study investigated preservation of digital information resources in Federal University Libraries in North Western States of Nigeria. To achieve the objective of the study, four research questions were constructed. A qualitative research methodology was used; purposive sampling was used for the study, the instrument used for data collection was the structured interview. The responses from the respondents who are staff of the digitization unit were analyzed descriptively using tables. The result of the findings showed that the most popular information resources generated and preserved are theses dissertation, preprint and post print journals. External hard drives, CD-rom/DVD and computer hard disk are the common storage media used for preservation in the libraries studied. It was also discovered that migration and use of standard are the popular strategies used for preservation. The study discovered that the major challenges in preservation of digital information resources include; lack of infrastructure, technological obsolescence, poor maintenance culture, inadequate power supply and inadequate fund. The study concludes that even though some form of preservation is carried out on digital information resources in libraries studied but yet not effectively and efficiently done. In view of this a number of recommendations were made including providing different types of digital information resources such as record inventions, technical report, use of mirror server, use of strategies such as emulation, refreshment ,constant upgrades of hardware and software.