COMPARATIVE ANALYSIS OF ANTIMICROBIAL STRENGTH OF THREE MOST COMMON ANTIBIOTICS USED IN ENUGU
(CASE STUDY OF ANTIBIOTICS DRUGS BROUGHT IN OBIAGU)
By
OSAGIE IZEHIESE BEAUTY
Presented To
Department of Science Technology
ABSTRACT
In comparing the antimicrobial strength of three most common antibiotics, which includes: streptomycin chloranphenicol and gentarccin.
Samples of urine and high vaginal swab (H.V.S) were collected from park lane Enugu. The organisms isolated were pure culture of staphylococcus aureus and Escherichia coli
Sensitivity test was carried out with the use of sensitivity disk containing various minimum inhibitory concentration of the different antibiotics.
The result obtained shaved that gentamicn was more effective followed by chloramphenicol while some organisms shaved resistant to streptomycin.
LIST OF TABLE
TABLE 1 NUTRIENT AGAR
TABLE 2 BLOOD AGAR
TABLE 3: ANTIBIOTICS AGAINST SYAPHYLOCOCCUS AUREUS
TABLE 4: ANTIBIOTIC AGAINST ESCHERICHIA COLI
LIST OF FIGURES
FIGURE 1: STREPTOMYCIN
FIGURE 2: CHLORAMPHENICOL
FIGURE3: SENSITIVITY TEST ON STAPHYLOCOCCUS AUREUS
FIGURE 4 SENSITIVITY TEST ON ESCHERICHIA COLI
FIGURE 5: STAPHYLOCOCCUS AUREUS AGAINST ANTIBIOTICS
FIGURE 6: ESCHERICHIA COLI AGAINST ANTIBIOTICS
TABLE OF CONTENT
Title page
Certification
Dedication
Acknowledgement
Abstract
List of tables
List of figures
Table of contents
CHAPTER ONE
1.0 Introduction
1.1 Historical background
1.2 Aims and objective
1.3 Hypothesis
1.4 Statement of problem
1.5 Scope of study
1.6 Limitation of study
CHAPTER TWO
2.0 Literature review
3.1 Procurement of antibiotics
3.1.1 streptomycin
2.1.2 Chloramphenicol
2.1.3 Gentamicin
2.2 Antimicrobial activity in vitro
2.3 Antimicrobial activity in vivo
2.4 Resistance to antimicrobial drugs
2.5 Factors affecting antimicrobial activity
2.6 Clinical use of antibiotics
2.7 Characteristic of antibiotics
CHAPTER THREE
3.0 Materials and method
3.1 Sample collection
3.1.1 Media composition
3.1.2 Direction for the preparation of nutrient agar
3.1.3 Direction for the preparation of blood agar
3.1.4 Material used for the prewritten of media
CHAPTER FOUR
4.0 Isolation and identification procedures
4.1.1 Isolation and identification of staphylococcus aureus
4.1.2 Isolation and identification of escherichia coli
4.2 Sensitivity test
CHAPTER FIVE
5.0 RECOMMENDATION
5.1 CONCLUSION
REFERENCES
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