This study was designed to investigate lecturer?s awareness, readiness and level of self-efficacy as determinant of micro-blogs use for teaching in Kaduna State universities.The influence of gender and experienced were also analysed. The study had nine specific objectives, nine research questions, and six null hypotheses which were formulated and tested at 0.05 level of significance. A total of 285 lecturers were surveyed, using questionnaires. The results of the survey were analysed using descriptive statistisc, Mann-Whitney and Kruskal-Wallis Test. The results of the survey based on the hypotheses tested revealed that most lecturerswere aware of the use of micro-blogs for teaching in tertiary institution in the State with cumulative mean of (3.11) outweighs the decision mean (2.50). Respondents show readiness in the use of micro-blogs as means of teaching in tertiary institutions as evident as evident from the fact that cumulative mean was (3.8) high. The result also revealed that lecturers self-efficacy was high based on the fact that cumulative mean (3.25) was higher than the decision mean of (2.50). Hypotheses one, two and three revealed that there is no significant difference between male and female lecturers? awareness, readiness and self-efficacy in using micro-blogs for teaching while null hypotheses four, five and six revealed that there was significant differences in lecturers year of experience on the awareness (10.730), readiness (14.778) and self-efficacy (6.541) on the use of micro-blogs for teaching at 0.05% level of significant in the State.The result therefore concluded that gender has no influence on the awareness, readiness and self-efficacy while years of experience influence on the awareness, readiness and utilization on the use of micro-blogs for teaching in tertiary institutions in Kaduna State. Based on the findings, it is recommend that lecturers should be given all necessary assistance that will aid them to identify and exploits the use of micro-blogs in their subject area as well as enlighten and educating them on its usage by the university stakeholders.