Due Co the oxytetracycline's usefulness and availability, its effect in a local food animal (Chicken: Gallus domesticus L) was investigated, and the residual drug level in the tissues, assessed. Seventy-two young broiler-type chick (of both sexes) were used for the experiment. They were herded in batches of 12 as groups A - F. The groups were given feed (Sanders (R) miixed with the Terratnycin (R) poultry Formula at 300, 200, 150, 50 and 0 g/ton for the groups A - F, respectively, and served water: at lib. They were housed in a slat-litter partitioned illuminated cages, and sacrifised at 3, 6, 9 and 12 weeks intervals. Analysis for the oxytetracycline levels in the muscle, kidney, liver, fat, intestinal contents and the blood were done; using ultravioletvisible spectroscopy. The tissue samples were also evaluated by thin layer chromatography and colour-spot-tests