This study titled "Evaluation of resource management in Osun state secondary schools, Nigeria" was necessitated due to inadequate supply of teachers, poor attitude of staff to work, incessant wage strike and poor infrastructural facilities among others. The objectives of the study were to find out the extent to which human, material, financial and time resources were effectively managed in secondary schools in Osun state. To this effect, the descriptive survey method was adopted for investigation and data collection. The population for the study was 3,961 which covered all the 3,490 teachers, 329 principals, 70 Ministry of Education Officials and 72 Zonal Education Officials in the state. The sample size of the entire population was collected through a stratified random procedure where 33 secondary schools were randomly selected; 11 each from Osun East, Central and West senatorial districts with a total number of 258 teachers, 33 principals, 30 Zonal Education Officials and 30 Ministry of Education officials which gave a total of 351 respondents. For the purpose of the study, an open ended questionnaire which was validated by experts in the department was pilot tested and gave a reliability co-efficient of 0.978 which signified that the instrument was reliable for the study. A total of 351 copies of questionnaire were administered to the respondents out of which 322 were returned fully completed. The major findings of the research revealed that teachers were in short supply in the state. Moreover, the available teachers were not posted to schools early which can lead to a distorted academic progress in the schools in Osun state. Ideally, the number of teachers needed for a new session should be planned, determined and posted before a new session starts if the objectives of the school must be achieved. It was also discovered that renovation of structures were not properly supervised by the stakeholders, which might pose danger to the well-being of learners in the schools concerned. Based on these findings, it was recommended that adequate number of teachers should be employed and posted to schools early so that the goals and objectives of the schools can be achieved. In addition, there is need for close monitoring of school structures to ensure safety of human lives. The Ministry of Education should ensure close supervision of school resources so that commensurate provisions of human, material and financial resources are guaranteed. This would help to meet the divergent needs of the schools in the state.